On the use of modern computers and supercomputers in Multithreaded mode

With the use of modern computers or supercomputers can one take full advantage of the capabilities of multithreaded mode?, that is, in order to fully use the power of Multithreaded mode, could this be achieved with the use of modern computers or supercomputers?

_Geant4 Version:_11.2.1
_Operating System:_Windows 10
_Compiler/Version:_Visual Studio 2022
_CMake Version:_3.29.0-rc2

Yes, but only with event-level Posix threading. Not GPUs. There is a G4 example for MPI.

OK thank you for answering. I have other questions: How do I set event-level Posix threading in my simulation?, Can this be set with commands in the Geant4 UI?, Or does this have to be set in CMake or where do I set that?. What do you mean by “No GPUs”?; Is the Geant4 example for MPI designed to run only on modern computers or supercomputers?. Thanks in advance